Viral Isolation and Enrichment Solutions

Conventional virus enrichment methods, such as ultracentrifugation, typically require specialized equipment and involve complex, time-consuming workflows that limit laboratory efficiency. IMPMM has developed an innovative viral isolation and enrichment technology that requires only a standard laboratory centrifuge to achieve rapid and efficient virus enrichment. This approach significantly improves detection sensitivity and positive detection rates, providing a convenient and reliable solution for the analysis of low viral load samples.

Solution Overview

Application Areas

Many clinically important viruses, including HIV, HBV, and HCV, have particle sizes in the 20–140 nm range, which largely overlap with the size distribution of extracellular vesicles. Leveraging this characteristic, Supbio’s Exosome Isolation Kit (click to view product information) enables efficient co-enrichment of extracellular vesicles and viral particles, achieving viral recovery rates above 95%. The method is simple and rapid to perform, significantly increasing viral concentration in samples and improving the sensitivity and reliability of downstream nucleic acid extraction and detection.

Accurate Viral Load Quantification

Viral enrichment increases viral particle recovery in low viral load samples, reducing false negatives and enabling more sensitive and reliable qPCR-based viral load quantification.

Genotypic Drug Resistance Analysis

Enhanced viral enrichment improves amplification success and enables detection of low-frequency resistance mutations, supporting accurate genotypic resistance profiling and informed treatment decisions.